StressCovidV1, Main, Exploration, bibRecord, 001A43

[Epidemiological actualization of the avian influenza. New analysis of sanitary risk].

Identifieur interne : 001A43 ( Main/Exploration ); précédent : 001A42; suivant : 001A44

[Epidemiological actualization of the avian influenza. New analysis of sanitary risk].

Auteurs : Guillermo Suárez Fernández

Source :

Anales de la Real Academia Nacional de Medicina [ 0034-0634 ] ; 2009.

RBID : pubmed:20432671

Descripteurs français

KwdFr :
- Animaux, Grippe chez les oiseaux (virologie), Grippe chez les oiseaux (épidémiologie), Grippe humaine (virologie), Grippe humaine (épidémiologie), Humains, Oiseaux, Prévision, Sous-type H5N1 du virus de la grippe A (génétique), Évaluation des risques.
MESH :
- génétique : Sous-type H5N1 du virus de la grippe A.
- virologie : Grippe chez les oiseaux, Grippe humaine.
- épidémiologie : Grippe chez les oiseaux, Grippe humaine.
- Animaux, Humains, Oiseaux, Prévision, Évaluation des risques.

English descriptors

KwdEn :
- Animals, Birds, Forecasting, Humans, Influenza A Virus, H5N1 Subtype (genetics), Influenza in Birds (epidemiology), Influenza in Birds (virology), Influenza, Human (epidemiology), Influenza, Human (virology), Risk Assessment.
MESH :
- epidemiology : Influenza in Birds, Influenza, Human.
- genetics : Influenza A Virus, H5N1 Subtype.
- virology : Influenza in Birds, Influenza, Human.
- Animals, Birds, Forecasting, Humans, Risk Assessment.

Abstract

A review has been made of the present epidemics of Avian Influenza, which originated in the year 2003 in Southeast Asia, and expanded thereafter to 60 countries in three continents (Asia, Africa and Europe), with more than 3000 outbreaks and millions of affected poultry, and 80% mortality. Special emphasis is made on the genetic variability of the etiological agent, the Orthomyxovirus A H5N1, which may accumulate point mutations in several genes distributed in eight segments, and especially in the gene which encodes the hemagglutinin (HA). Stress is made in a recent mutation in the gene which encodes polymerase PB2, which determines the substitution of one amino acid, and is associated to the virulence of the virion, enabling it to adapt to the upper human respiratory tract and to replicate in this area. This mutation dangerously approaches the virus A H5N1 to a possible interhuman transmission and to become a pandemic virus, possibly in the near future. The present knowledge and the social structure would permit to content and control the pandemic state with the due speed and efficacy.

PubMed: 20432671

Affiliations:

Le document en format XML

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<term>Prévision</term>
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<term>Évaluation des risques</term>
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<front><div type="abstract" xml:lang="en">A review has been made of the present epidemics of Avian Influenza, which originated in the year 2003 in Southeast Asia, and expanded thereafter to 60 countries in three continents (Asia, Africa and Europe), with more than 3000 outbreaks and millions of affected poultry, and 80% mortality. Special emphasis is made on the genetic variability of the etiological agent, the Orthomyxovirus A H5N1, which may accumulate point mutations in several genes distributed in eight segments, and especially in the gene which encodes the hemagglutinin (HA). Stress is made in a recent mutation in the gene which encodes polymerase PB2, which determines the substitution of one amino acid, and is associated to the virulence of the virion, enabling it to adapt to the upper human respiratory tract and to replicate in this area. This mutation dangerously approaches the virus A H5N1 to a possible interhuman transmission and to become a pandemic virus, possibly in the near future. The present knowledge and the social structure would permit to content and control the pandemic state with the due speed and efficacy.</div>
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Serveur d'exploration Stress et Covid

[Epidemiological actualization of the avian influenza. New analysis of sanitary risk].

[Epidemiological actualization of the avian influenza. New analysis of sanitary risk].

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration Stress et Covid
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